---
description: Compare SentinelOne vs Microsoft Defender for Office 365 to learn about each of the product's price, benefits and disadvantages. Choose the best software for your business in Australia.
image: https://gdm-localsites-assets-gfprod.imgix.net/images/capterra/og_logo-e5a8c001ed0bd1bb922639230fcea71a.png?auto=format%2Cenhance%2Ccompress
title: SentinelOne vs Microsoft Defender for Office 365 Comparison - Capterra Australia 2026
---

Breadcrumb: [Home](/) > [Endpoint Protection Software](/directory/30907/endpoint-protection/software) > [SentinelOne \<span\>vs\</span\> Microsoft Defender for Office 365](https://www.capterra.com.au/compare/152564/219685/endpoint-protection-platform/vs/microsoft-defender-for-office-365)

# Compare SentinelOne vs Microsoft Defender for Office 365

Canonical: https://www.capterra.com.au/compare/152564/219685/endpoint-protection-platform/vs/microsoft-defender-for-office-365

> Detailed comparison between SentinelOne and Microsoft Defender for Office 365. Check ratings, reviews, pricing, and features to make the best decision for your business.

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## At a Glance

| Metric | SentinelOne | Microsoft Defender for Office 365 |
| **Overall rating** | 4.8/5 | 4.6/5 |
| **Total Reviews** | 109 | 235 |
| **Starting Price** | USD 179.99 | - |
| **Free Trial** | Yes | No |
| **Free Version** | No | - |
| **Deployment** | Cloud, SaaS, Web-based, Mac (Desktop), Windows (Desktop) | Cloud, SaaS, Web-based |
| **Support** | Email/Help Desk, FAQs/Forum, Knowledge Base, Phone Support, 24/7 (Live rep), Chat | - |
| **Training** | In Person, Live Online, Webinars, Documentation | Live Online, Webinars, Documentation, Videos |

## Best for

### SentinelOne

Mid-sized businesses, large enterprises, and public sector organizations  needing AI-driven, autonomous cybersecurity and endpoint protection with real-time threat detection and response.

### Microsoft Defender for Office 365

DevOps and Security Operations (SecOps) teams&#10;Security engineering teams&#10;IT teams&#10;CISOs and CTOs&#10;Red, Blue, and Purple Teams&#10;CSIRT \&amp; forensic team&#10;Microsoft 365 administrators

## Key features

### SentinelOne

- AI/Machine Learning
- API
- Access Controls/Permissions
- Access Management
- Activity Tracking
- Anomaly/Malware Detection
- Application Security
- Dashboard
- Monitoring
- Network Mapping
- Policy Management
- Real-Time Monitoring
- Real-Time Reporting
- Status Tracking
- Threat Response
- Vulnerability Protection
- Whitelisting/Blacklisting

### Microsoft Defender for Office 365

- Access Controls/Permissions
- Email Routing
- Filtering
- Policy Management
- Real-Time Monitoring
- Threat Protection
- Threat Response
- Whitelisting/Blacklisting

## Links

- [View SentinelOne Profile](https://www.capterra.com.au/software/152564/endpoint-protection-platform)
- [View Microsoft Defender for Office 365 Profile](https://www.capterra.com.au/software/219685/microsoft-defender-for-office-365)
- [View Original Comparison](https://www.capterra.com.au/compare/152564/219685/endpoint-protection-platform/vs/microsoft-defender-for-office-365)

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